Tycho Heimbach | Fellow and Labhead Novartis Pharmaceuticals Corporation
Dr. Tycho Heimbach is an Associate Director at Novartis Institutes for BioMedical Research in East Hanover, NJ. In his current role, he chairs a global team which reviews and makes recommendations for formulation and PK/PD strategies for all disease areas within the global DMPK function. He also serves as a representative on a global food-effect and IVIVC working groups where the main objective is to strengthen the biopharmaceutical sciences between different line functions at Novartis. His key responsibilities include bioavailability, formulation and ADME studies needed for regulatory submission in all major disease areas toward FIH studies. Tycho’s industrial work experience (20 years) encompasses various roles at Pfizer in formulation development, biopharmaceutics and DMPK departments and at BASF in polymer-chemistry R&D.
Dr. Heimbach has been involved in the American Association of Pharmaceutical Scientist (AAPS) for more than 7 years serving as a chair/co-chair of the prodrug focus group. He has served treasurer/secretary and is currently the Vice Chair of the Physical Pharmacy and Biopharmaceutics (PPB) section.
Dr. Heimbach received his B.S. in Chem. Engineering from the FH Druck College in Stuttgart, Germany and his M.S. in polymer science from the University of Detroit-Mercy, followed by his second M.S. (1997) and Ph.D. in Pharmaceutics (2003) from the University of Michigan. Dr. Heimbach has been an invited speaker to more than 15 national and international conferences and workshops speaking on topics of prodrugs, oral absorption, formulation-dependent human PK/PD projection and IVIVC.
Share this
Appearances at this years' conference:
Thursday 24 May 2012- Day Two
@ 09.00
Proven predictive preclinical models for projections of anticipated human dose, PK/PD and food effect for Optimized Clinical Outcome
Application of “proven” animal PK and PBPK scaling approaches focusing on detailed case examples.
Successful selection of human doses for FIH studies and beyond
Identification of food effect risks, and projections of food-effects via application of the BDDCS classes.
Modeling and simulation as meaningful tools in designing PK/formulation/ADME as well as species scaling toward FIH studies: Specific formulation strategies, and proven modeling approaches that can be used when facing different BCS/BDDCS class compounds will be covered.
› Tycho Heimbach, Fellow and Labhead, Novartis Pharmaceuticals Corporation