Wednesday 23 May- stream one

Day one- Wednesday 23 May ›

Wednesday 23 May- stream one ›

Wednesday 23 May 2012- stream two ›

Day Two: Thursday 24 May ›

last modified: 29 May '12

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Biomarkers in discovery

11.10am

Opening remarks from the chair

11.15am

Integrating technologies in targeted medicine biomarker strategies

Dr Michael Burczynski at Biomarkers World Europe

› Dr Michael Burczynski, Executive Director, Head of Integrated Clinical Biomarker Technologies, Bristol-Myers Squibb

11.45am

Using receptor occupancy in the drug discovery process

› John Atack, Senior Research Fellow, Neuroscience, Johnson & Johnson

12.15pm

Bioanalytical applications for biomarker discovery and validation

Chris Roberts

Chris Roberts, Ph.D., is Director of the Research Solutions Bioinformatics Team in the Informatics and Analysis Department at Merck Research Laboratories and is based at Merck's Boston MA research facility. He leads at team of bioinformaticists...

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› Chris Roberts, Director, Research Solutions and Bioinformatics, Merck Research Laboratories

12.45pm

Lunch

1.45pm

Keeping the promise: Pathway-based identification of patient stratification and proof of mechanisms for targeted kinase therapeutics

Cloud Paweletz

Dr. Paweletz has been involved in basic and clinical research over his entire career, and has extensive experience at NIH and in industry. He has special expertise in cancer, proteomics, and systems biology. His most recent experience has been at...

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› Cloud Paweletz, Research Fellow, Merck

2.15pm

Managing intra-subject variability of human CSF Biomarker levels in clinical studies

Dr. Jinhe Li

Research on Alzheimer's disease and therapy at Harvard, Pharmacia, Pfizer, and Abbott. Drug discovery experience from target discovery to preclinical pharmacology, translational research, and clinical biomarker studies. Co-discovered Alzheimer's...

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› Dr. Jinhe Li, Sr. Manager, External Imaging, Abbott

2.45pm

Validation of immunoassay for protein biomarkers to support pre-clinical and clinical studies

Dr Marie-Anne Valentin

Marie-Anne Valentin received a PhD in Pharmacology from the University of Nancy (France) in 2001 and used a broad technology portfolio to study protein function during subsequent postdoctoral fellowship at the University College of London (UK). In...

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› Dr Marie-Anne Valentin, Biomarker program leader, Novartis Pharma AG

3.15pm

Afternoon refreshments

3.45pm

What are we measuring, how much of it is there and why does it matter?

Richard Welford

Richard leads a lab focused on the application of mass-spectrometry to achieve high confidence read outs of biomarkers across the R&D organization at Actelion. The work covers both protein and metabolite measurements. The Lab is embedded in the...

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› Richard Welford, Lab Head, Translational Science, Actelion

4.15pm

Panel: Discovering biomarkers of clinical utility

Dr Maria Hernandez Fuentes

Dr Hernandez-Fuentes completed an MD in Universidad Complutense and her PhD in Immunology in Universidad de Alcalá, both in Madrid, Spain. In 1998 she came to the UK to do her first post-doc with Professor Robert Lechler, then at Imperial...

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